Risek 14 Capsules 40 mg
Inhouse product
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AED32.00 -
AED25.00
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AED8.00
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AED354.00
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AED25.00
Reviews & Ratings
Medical Description
Proton pump inhibitor used in the treatment of Gastroesophageal reflux disease, Helicobacter pylori eradication, treatment and secondary prevention of peptic ulcer disease.
Indication & Usage
-Gastroesophageal reflux disease: Initial therapy: Mild/intermittent disease (<2 episodes/week) and no evidence of erosive esophagitis: Oral: 10 mg once daily; can increase to 20 mg once daily after 4 to 8 weeks if necessary. Discontinue once asymptomatic for 8 weeks, Severe and/or frequent symptoms (≥2 episodes/week) and/or erosive esophagitis: Oral: 20 to 40 mg once daily; once symptoms are controlled, continue for at least 8 weeks. -Helicobacter pylori eradication: Oral: 20 mg or 40 mg twice daily as part of an appropriate combination regimen with antibiotics. -Primary prevention of nonsteroidal anti-inflammatory drugs (including aspirin)–induced ulcers: Oral: 20 mg once daily for the duration of high-risk NSAID use. -Treatment and secondary prevention of Peptic ulcer disease: Uncomplicated ulcer: Oral: 20 to 40 mg once daily. Duration depends on the size, location, and cause of the ulcer and ranges from 4 to 8 weeks. In patients with refractory or recurrent disease, may increase the dose to 20 to 40 mg twice daily. Complicated ulcer (perforation, penetration, or gastric outlet obstruction): Oral: 40 mg twice daily for 4 weeks, followed by 40 mg once daily. Duration depends on the location and etiology of the ulcer. -Stress ulcer prophylaxis in select critically ill patients: Oral or via NG tube: 40 mg once daily or 40 mg initially, then another 40 mg dose given 6 to 8 hours later, followed by 40 mg once daily. Discontinue prophylaxis once critical illness and modifiable risk factors have resolved -Erosive esophagitis: Infants, Children, and Adolescents: Oral: 3 to <5 kg: 2.5 mg once daily. 5 kg to <10 kg: 5 mg once daily. 10 kg to <20 kg: 10 mg once daily. ≥20 kg: 20 mg once daily. Maintenance dose: Children and Adolescents: Oral: 5 kg to <10 kg: 5 mg once daily. 10 kg to <20 kg: 10 mg once daily. ≥20 kg: 20 mg once daily. Duration of therapy is dependent on age: Infant duration is up to 6 weeks and children and adolescent duration is 4 to 8 weeks.
Dosage & Administration
-Administer 30 to 60 minutes before a meal; best if taken before breakfast. If administered twice daily, the first dose should be administered before breakfast and the second dose before dinner. -Optimal pre endoscopic PPI therapy is uncertain. Some experts suggest initiating high-dose IV PPI with continuous or intermittent dosing in patients with suspected active upper GI bleed prior to endoscopy. Following endoscopy, for patients with high-risk stigmata of recent bleeding (eg, active bleed, visible vessel, adherent clot), a continuous infusion of an IV PPI for at least 72 hours before transitioning to an oral PPI is recommended.
Side Effects
-omeprazole, may increase risk of enteric infections in adult and pediatric patients, including gastroenteritis and Clostridium difficile associated diarrhea (CDAD). Long-term use of acid suppressive therapies, including omeprazole, may result in reversible vitamin B12 deficiency. Respiratory system disorder, skin rash abdominal pain, constipation, diarrhea, flatulence, nausea, vomiting, dizziness, headache, asthenia, back pain, cough, upper respiratory infection.
Safety Advice
-In patients who have received continuous therapy for >6 months, gradually taper therapy until discontinuation to avoid worsening or rebound symptoms. If the patient is receiving 40 mg once or twice daily, decrease the dose by 50% every week. For patients receiving twice-daily dosing, the first dose reduction can be achieved by decreasing to once-daily. -Hepatic Impairment: Adult: Mild to severe impairment: 10 mg once daily when used for maintenance of healing of erosive esophagitis. -Should not be used in case of Hypersensitivity (eg, anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute tubulointerstitial nephritis, urticaria) to omeprazole, -Prolonged treatment (≥2 years) may lead to malabsorption of dietary vitamin B12 and subsequent vitamin B12 deficiency. -Incase of overdose, be ready to tell or show what was taken, how much and when it happened, and seek immediate medical attention. For additional information call us on 16676. Always tell your physician your detailed medical history.
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AED32.00
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AED25.00
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AED8.00
-
AED354.00
-
AED25.00
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